1B-LSD | 100mcg Drop Bottle

1B-LSD (1-Butanoyl-d-lysergic acid diethylamide) is a molecule substance of the Lysergamide family. It is comparable to and 1P-LSD and other Lysergamides. 1B-LSD surfaced on the research chemical market in 2018. Very little data exists about the research chemical or about who discovered it.

All Lysergamides are isolated from a fungus called ergo. Ergot contains compounds known as ergot alkaloids, each containing a system called the tetracyclic ergoline ring system. Modifying the ergoline ring system in the N1 position are the most frequently performed changes you’ll see. Indole nitrogen is easily accessible for reactions and additions. 1B-LSD is structurally similar to 1P-LSD and named for the butyryl group bound to the nitrogen of the polycyclic indole group. In contrast to LSD, 1B-LSD has an additional N1-butyryl group.

Like other acyl homologs (such as 1P-LSD), 1B-LSD is deacylated via CYP1A2 and CYP3A4 by the elimination of the butyric acid (the “B” in 1B-LSD). Why use butyric acid to begin with? Butyric acid is a fatty acid that helps break down the fibre. When the butyric acid is eliminated, you will end up with a different compound. 

1-akylated lysergamide derivatives are useful research chemicals. Lysergic acid N,N-dimethylamide is derived from lysergic acid amide, not LSD. Following this logic, we can assume that the 1-alkyl and 1-acyl derivatives of the N,N-dimethyl isomer do not fall under controlled substance laws. Ergo, we can modify the ergoline ring system in the N1 position to create derivatives like 1B-LSD.